What Are Vaccines?

Vaccines safely prepare your immune system to fight dangerous germs before you get sick.

  • A vaccine contains harmless parts of a virus or bacteria, such as proteins, sugars, or weakened or inactivated forms of the germ.
  • These pieces are called antigens, which help your immune system recognize the invader.
  • When vaccinated, your immune system identifies these foreign pieces and starts building a defense.
  • It produces antibodies that can attack the real germ if it ever enters your body.

How Vaccines Train Your Immune System

Vaccines help your immune system build long-term protection using memory cells.

  • After vaccination, your white blood cells activate two teams:
    • B cells make antibodies to block and neutralize germs.
    • T cells destroy infected cells and help coordinate the immune response.
  • Once trained, your immune system creates memory cells that stay in your body for months, years, or even a lifetime.
  • If the real germ enters later, your memory cells respond quickly, stopping the infection before it becomes serious.

Fun Facts

Here are some interesting facts about vaccines:

  • The first vaccine was created by Edward Jenner in 1796 to protect against smallpox.
  • Herd immunity helps protect people who can’t get vaccinated, like newborns or people with certain health problems.
  • Some vaccines, like the tetanus shot, need booster doses every 10 years to keep working.
  • mRNA vaccines (like some COVID-19 vaccines) teach your cells to make a tiny part of the virus so your immune system can learn to fight it.

Review

Let’s quickly recap what we learned about vaccines:

  • What do vaccines introduce to help train your immune system? Antigens
  • What kind of cells make antibodies after vaccination? B-Cells
  • What special cells remember how to fight the germ? Memory Cells
  • Which disease did the first vaccine protect against? Smallpox

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